PHYTOCHEMICAL ANALYSIS AND ANTIOBESITY PROPERTIES OF ENDEMIC Jurinea brevicaulis Boiss.

Obesity, defined as New World Syndrome, causes global health problems and big economic losses. Natural products have gained increasing importance because of their antiobesity potency. The genus Jurinea Cass. with approximately 200 described species worldwide has been traditionally used a therapeutic agent for colic, fever, gout rheumatism. aim this study was to analyze the volatile components, determine phenolic compounds evaluate α-amylase, α-glucosidase, lipase inhibitory activities endemic plant brevicaulis Boiss. widely solid-phase microextraction technique (SPME) employed Gas Chromatography-Mass Spectrometry (GC/MS) analysis components. Quantitative performed using Reversed-Phase High-Performance Liquid Chromatography (RP-HPLC). A total 19 components were specified o-cymene (10.60 %), β-bisabolene (9.30 sesquicineole (57.5 %) different terpenes major According RP-HPLC analysis, sinapic acid, p-coumaric acid quercetin determined species. IC50 values 36.59 ± 2.37 μg/mL 42.56 2.83 α-amylase α-glucosidase assays, respectively. value found 50.31 3.75 inhibition analysis. In conclusion, it that J. included diverse three effect potential, which highlights up-and-coming candidate natural product source be against obesity.